- Estimation of Mutation and Selection
Most mutations are deleterious and selected against. Loss of a mutant allele is calculated by comparing gene frequencies in successive generations to predict fitness. For question below, explain your answers in detail.
Deleterious recessive mutant gene calculation
- What is the maximum frequency the mutant gene for Fabry’s Syndrome can increase to, at equilibrium? Fabry’s Syndrome, Aut Rec, Fitness of 0, Incidence of 1/1,000,000