Prompt/Topic: Changes in electrolytes or amount of fluid in the ICF or ECF affect every system in the body. Sometimes chemicals or infectious organisms can result in extreme irritation of the cells lining the large intestine. In response to this irritation, these cells may secrete sodium into the large intestine. Describe the changes that would occur in the ICF if sodium was excreted from the intestinal lining into the large intestine. How would the decreased sodium and water in the IF affect blood plasma? How would this change affect arterial blood pressure? How would the ICF in the cells lining the large intestine be restored to their original state?